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neuroplasticity

memory neurobiology
by
Livia Farkas (author)  

First published: 6 August, 2026 | Last edited: 6 August, 2026 |🕒 Reading Time: < 1 minute | 🔗
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Neuroplasticity is the brain’s capacity to change its own wiring. Neurons form new synaptic connections, strengthen existing ones, and, through synaptic pruning, remove the ones that don’t get used. This process is most active during childhood and adolescence, but it continues throughout adulthood and old age.

In neurodivergent brains, plasticity works differently, but that doesn’t mean it works less well.

  • Autistic brains can show hyperplasticity, which is a heightened capacity for synaptic change in certain domains, which may contribute to intense skill acquisition and deep knowledge development in areas of strong interest.1
  • In ADHD, stimulant medication appears to influence brain structure over time, suggesting it may support the underlying conditions the brain needs to adapt, beyond managing symptoms in the moment.

For late-identified adults, one of the most common questions is whether it’s too late for any of this to change anything. Luckily, according to neuroscience, it is not.

You can still produce physical changes in your brain structure over time. Everything you do, including the strategies you build, the environments you choose, the sleep you protect, and the understanding you develop about how your own brain works, all add up.

And you can practice habits that support the process:

  • aerobic exercise increases production of brain-derived neurotrophic factor (BDNF), a protein involved in neuronal survival and new synaptic connections;
  • good quality sleep is when the brain consolidates learning and clears metabolic waste;
  • and adequate nutrition provides the raw materials for neurotransmitter production that plasticity needs to operate.

For a fuller picture of how neuroplasticity works in neurodivergent brains, including the research on exercise, sleep, and what medication does to brain structure over time, see our comprehensive entry on the neurodivergent brain.

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References
1↑ Oberman, L.M. & Bhatt, P.P. (2023). Atypical cortical plasticity as a biomarker and core pathophysiological mechanism in ASD. Autism Research, 17, 222–237.

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Related Glossary Terms

The neurodivergent brain

The brain is the organ behind every neurodivergent trait you experience — from how you pay attention to how you process emotion to how you sleep. Neurodivergent brains use the same basic structures and chemical messengers as any brain, but the tuning is different: different dopamine activity in reward circuits, different balance between excitatory and inhibitory signalling, different default mode network behaviour.

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the mTOR pathway

The mTOR pathway is a signalling system inside every cell that regulates the balance between building new structures and recycling old ones. In autistic brains, this pathway runs hotter than typical, suppressing the cell's internal cleanup processes. Up to 58% of autism-associated genes relate to this pathway, making it a point of convergence where many different genetic routes produce similar outcomes — from differences in synaptic pruning and sensory processing to neuroinflammation and the balance between excitatory and inhibitory brain signalling.

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vagus nerve

The vagus nerve is a bundle of nerve fibres in your body. It runs from the brainstem down through the neck and into the chest and abdomen. It branches out to the heart, lungs, airways, stomach, liver, intestines, and most of the digestive tract. It is the longest cranial nerve in the body. Roughly 80% of what it carries is sensory information travelling upward. The vagus nerve reports to your brain about what is happening in your organs. In recent years, the vagus nerve has become a fixture of wellness content. Many techniques, including cold showers, humming, and gargling, are promoted as ways to “stimulate” or “tone” it. Some of this is supported by research, but many of the easy-fix claims are exaggerated. And for neurodivergent people in particular, some of the advice is actively unhelpful.

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gut-brain axis

The gut-brain axis is the two-way communication system between your digestive tract and your brain. It runs on nerves, neurotransmitters, immune signals, and microbial chemistry, and it's a large part of the reason why so many neurodivergent people have persistent stomach problems which are often not even connected to their neurodivergence.

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About the Author

  • Livia Farkas

    Livia Farkas is an adult education specialist with a joy-centred approach and a sharp sense for simplifying complex ideas using silly visual metaphors.
    Since 2008, she's written 870+ articles, developed 294 distinct techniques, and co-created 8 online courses with Adam—with 5,302 alumni learning neurodivergent-friendly approaches to time management, goal setting, self-care, and small business management.
    Her life goal is to be a walking permission slip for neurodivergent adults.

    View all posts

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