the mTOR pathway
The mTOR pathway is a signalling system inside every cell that regulates the balance between building new structures and recycling old ones. In autistic brains, this pathway runs hotter than typical, suppressing the cell's internal cleanup processes. Up to 58% of autism-associated genes relate to this pathway, making it a point of convergence where many different genetic routes produce similar outcomes — from differences in synaptic pruning and sensory processing to neuroinflammation and the balance between excitatory and inhibitory brain signalling.





